Jan Beute Selected Research

Enoximone

6/2022	Oral enoximone allows the reduction and discontinuation of inhaled steroids and beta2 agonists in asthmatic children.
1/2021	PDE3-inhibitor enoximone prevented mechanical ventilation in patients with SARS-CoV-2 pneumonia.
1/2021	Evaluation of Real-Life Investigational Use of Enoximone in Asthma, the Third Step in Drug Repurposing: A Preliminary Report.
1/2021	Phosphodiesterase-3 Inhibitor Enoximone in SARS-CoV-2 Infection.
10/2020	(Oral) enoximone in asthma.
1/2018	A pathophysiological role of PDE3 in allergic airway inflammation.
9/2009	Levosimendan is superior to enoximone in refractory cardiogenic shock complicating acute myocardial infarction.

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Jan Beute Research Topics

Disease

3	Status Asthmaticus 06/2022 - 01/2018
3	Asthma (Bronchial Asthma) 06/2022 - 10/2020
2	Inflammation (Inflammations) 01/2020 - 01/2018
1	COVID-19 01/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Dyspnea (Shortness of Breath) 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Respiratory Insufficiency (Respiratory Failure) 01/2021
1	type 2C Congenital disorder of glycosylation 01/2020
1	Septic Shock (Toxic Shock Syndrome) 06/2010
1	Myocardial Infarction 09/2009
1	Cardiogenic Shock 09/2009

Drug/Important Bio-Agent (IBA)

7	EnoximoneIBA 06/2022 - 09/2009
2	Phosphodiesterase 3 InhibitorsIBA 06/2022 - 10/2020
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2018
1	Monoclonal AntibodiesIBA 06/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2022
1	Bronchodilator Agents (Bronchodilators)IBA 01/2021
1	GoldIBA 01/2021
1	Immunoglobulin E (IgE)IBA 01/2020
1	Substance PIBA 01/2020
1	Cyclic AMP (AMP, Cyclic)IBA 01/2018
1	IntegrinsIBA 01/2018
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2018
1	Simendan (Levosimendan)IBA 09/2009

Therapy/Procedure

3	Therapeutics 06/2022 - 01/2020
1	Artificial Respiration (Mechanical Ventilation) 01/2021
1	Catheters 06/2010